What EECP Does and Does Not Do ?
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By Dr. James B. DeStephens

It is very important to understand how EECP works to be able to appreciate then what it can
and cannot do. According to statistics EECP, in up to 85% of patients treated, significantly
and sometimes dramatically reduces the frequency and severity of angina heart pain. 20% of
the time angina symptoms go away completely and in 50% exercise tolerance at least doubles
before the onset of angina. EECP is able to do this through its ability to stimulate the
development of so called collateral circulation or “Natural Bypasses.” The Natural Bypasses
help to compensate for any circulation deficiencies that blocked
arteries may cause.
Most heart attacks, up to 85%, actually happen as a consequence of a blood clot which lodges
in a partially blocked artery. Two thirds of the time such a blood clot happens in an artery
that is not even critically blocked, that is, those arteries that are blocked between 40-60%.
Stents and bypass surgery are reserved for blockages in the range of 75% or worse but yet most
heart attacks happen in these lesser blocked arteries because it is easier for blood clots to
lodge in arteries that are blocked in this range.
The importance of all this is that as effective as EECP is in helping the heart grow new Natural
Bypasses, it does not open up blocked arteries and it does not stop blood clots from forming in
already partially blocked arteries.

Consequently, the extra circulation that EECP can provide essentially buys the coronary patient some
time to both identify and correct any of the risk factors that caused the blockages to occur in the
first place. If an artery blocks off completely whether it be due to a blood clot or not, heart damage
may occur. The size of the damage will be determined by how large an area of muscle was being supplied
by the artery and how effective the collateral circulation or Natural Bypasses may be. So that though
EECP cannot absolutely prevent a heart attack from occurring, its effectiveness can reduce the size of
the heart attack that may happen through its ability to at least partially, if not completely, make up
for any circulation deficit occurring from the blocked artery itself.
The long term benefit of EECP then will depend upon how effectively a patient has identified and
controlled those risk factors, to effectively halt, if not reverse the tendency, for coronary arteries
to develop these blockages.

So can EECP absolutely prevent a heart attack from happening? The answer is no. The blockages that
you had before EECP will still be there and they will still be susceptible to having blood clots form
in them or to have the natural sludging process continue slowly. If your EECP treatments have been
effective though, as evidenced by an increased exercise toleration and reduced angina frequency, then
you can be assured that the extra collateral circulation or “natural bypasses” that have been grown for
you will at least minimize the size of any heart attack that you might have if a blood clot should lodge
in a partially blocked artery as is the case in about 85% of those heart attacks that occur. That is
they occur as a consequence of a blood clot. Another way of thinking about this is that, EECP may be
able to get rid of all angina in a patient with an 80% blockage, but may not be adequate to avoid any
angina or even a small heart attack, if that 80% blockage becomes 100%, as a result of a blood clot or
the progressive slow blockage from cholesterol.
Perhaps an appropriate analogy might be as follows. If a family's house was burning and the fire
department was called and was able to save three of the five family members but that two people in
spite of their best efforts perished, would the remaining family thank the fire fighters for saving
the three or complain bitterly about why they could not save the other two. This is essentially the
same dynamic that occurs with EECP. In spite of a heart attack that might have occurred, how much
heart muscle was nevertheless saved as a consequence of the effective growth of some of these
“natural bypasses,” that like the firefighters would attempt to put out as much of the fire of
coronary disease as possible?
If you don’t control the risk factors that caused the blockages to occur in the first place then the
gradual sludging of your arteries will eventually overwhelm any benefits from EECP and your angina may
return or become worse.
As we have discussed before these risk factors include 1) High blood pressure 2) Smoking 3) No exercise
4) High stress life style 5) Diabetes 6) Elevated cholesterol 7) Elevated Homocysteine, Fibrinogen,
Lipoprotein (a) or C-Reactive protein in your blood. Each of these problems can be treated but you don’t
know to treat them unless you are aware that it is a problem for you. So please make sure that you know
the results of these tests.The noninvasive “Total Attack” approach that is recommended then includes EECP,
to grow new circulation to compensate for any blockages that might be already present, but must also include
an aggressive approach to the risk factors that caused the blockages to occur in the first place. Angioplasties,
stents and bypass surgery can then be reserved for those patients that are felt to be too unstable to wait
the necessary 7 weeks to complete a course of EECP and to begin the risk factor modification program.
If after a first course of EECP a patient is significantly improved, on the basis of frequency and severity
of angina symptoms, as well as improvement on an exercise test, but is still having some angina symptoms or
has not normalized his exercise test, then additional time with EECP will be recommended.
The understanding will be that if EECP has gotten rid of 50% or more of a patient’s symptoms but that some
symptoms still persist, then let’s stick with what seems to be working and try to get rid of even more angina
and perhaps continue to reduce some of the medications necessary to control it.